Alzheimer's and neurological disorders among those diseases which are being focused upon
NEW YORK – Eli Lilly 's blockbuster diabetes drug Mounjaro and weight-loss therapy Zepbound , as well as Novo Nordisk 's rival medicines Ozempic and Wegovy are being studied to see whether they can improve health in other ways.
Zepbound helped resolve moderate to severe obstructive sleep apnea in up to 52 per cent of patients in two late-stage trials, Lilly said on Friday.A study by the University of Copenhagen's Psychiatric Centre Rigshospitalet is investigating whether semaglutide, sold as Novo's Wegovy and Ozempic, can help reduce alcohol intake in 108 patients diagnosed with alcohol use disorder and obesity.Novo Nordisk has begun a trial testing semaglutide in patients with early Alzheimer's disease.
Researchers at the Chinese University of Hong Kong are testing Novo's semaglutide along with mechanical removal of clots in patients with strokes caused by the blockage of large blood vessels to the brain. The approach will be compared with standard therapy. The mid-stage study, opens new tab aims to recruit about 140 patients.Novo's Ozempic delayed the progression of chronic kidney disease in diabetes patients, cutting the risk of death from that and major cardiac events by 24pc.
Lilly's tirzepatide is being evaluated in a mid-stage study of chronic kidney disease in patients with obesity. Lilly plans to enrol up to 140 participants.Novo is testing semaglutide in a late-stage trial of patients with a common type of fatty liver disease called non-alcoholic steatohepatitis . The study is expected to enrol about 1,200 patients.
Lilly's tirzepatide helped up to 74pc of patients achieve absence of the disease with no worsening of liver scarring at 52 weeks, compared with 13pc of patients on placebo, in a mid-stage trial for the fatty liver disease formerly known as NASH and now called metabolic dysfunction-associated steatohepatitis, or MASH.
Health Conditions Eli Lilly Diabetes Drug Mounjaro Zepbound Novo Nordisk Ozempic Wegovy Alzheimer's Disease Alcohol Use Disorder Obesity
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